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(+)-Bicuculline

InhA, Func 485-49-4

(+)-Bicuculline ((+)-Bicuculline)

1 image

Catalog No. ABIN3220231

Quick Overview for (+)-Bicuculline (ABIN3220231)

Application

Inhibition Assay (InhA), Functional Studies (Func)

Purpose

Bicuculline is a light-sensitive competitive antagonist of GABAA receptors. It was originally identified in 1932 in plant alkaloid extracts and has been isolated from Dicentra cucullaria, Adlumia fungosa, Fumariaceae, and several Corydalis species.

Characteristics

Target: GABAR antagonist
Receptor: GABAA receptor

Purification

All the products are sent with COA, HPLC and NMR inspection report to guarantee the quality.

Purity

99 % +

Formula

C20H17NO6

Solubility

10 mM in DMSO
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Application Notes

Optimal working dilution should be determined by the investigator.

Restrictions

For Research Use only
Format

Solid

Storage

-20 °C

Storage Comment

For the majority of compounds, they could be dissolved in DMSO or other organic solvent.
Their stock solution can be stored at -20°C for up to 3 months and aliquoted for sampling convenience.
Several freeze/thaw cycles should not damage the activity of our small molecule products.
However, in many instances the aqueous solutions of some compounds need to be made fresh and cannot be stored. For these compounds, their solution should be prepared just before use and stored no longer than 24 hours.

Expiry Date

24 months
Background

Neuroscience

Molecular Weight

367.36 g/mol

CAS-No

485-49-4

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